Saturday, April 11, 2009
Friday, April 10, 2009
Therapeutic Massage Articles from Brenda hughey, LMT & Julie Van Tassel, LMT
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| © 2003 Saleeby Longevity Institute All Rights Reserved. |
Acupuncture article by Jane Gregorie, DOM, LAc
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| © 2003 Saleeby Longevity Institute All Rights Reserved. |
Friday, April 3, 2009
Celiac Disease (Gluten Intolerance)
Celiac Disease
by JP Saleeby, MD
The genetic malabsorptive disorder Celiac Disease (or celiac sprue) a condition where the body has an immunologic reaction to gluten may be more widespread than previously thought. It is estimated that one in 300 Americans have celiac disease. Since this condition can manifest itself from infancy to old age it is sometime overlooked or undiagnosed mainly due to low suspicion and its protean presentation. Symptoms may fall on a continuum from mild to severe, but there are certain key symptoms and signs that should trigger a complete work up for this disorder.
Celiac disease is an inherited disorder and results when gluten proteins from many of the grains we eat spark an immune reaction resulting in a malabsorptive digestive disorder.
Celiac disease often causes diarrhea, fatigue, borborygmus (rumbling stomach), abdominal pain, weight loss, distention of the abdomen, flatulence and iron deficiency anemia. Additionally, signs that present on examination of a patient are a skin disorder called dermatitis herpetiformis, aphthous ulcers (canker sores), low blood counts (anemia), with Diabetes mellitus (Type I) and autoimmune Thyroid disease as associated illnesses. The skin eruptions know as dermatitis herpetiformis is almost pathognomonic for celiac disease as those who present with it should be screened for it is found in up to 20% of patients with celiac disease. Under or misdiagnosis is certainly a problem. According to one study up to 36% of celiac patients were misdiagnosed as having irritable bowel syndrome until the true diagnosis was realized. Left untreated celiac disease can ultimately lead to osteoporosis and intestinal lymphoma.
When it is suspected there are serum (blood) tests that should be ordered first and they include immunoglobulin A (IgA) tissue transglutaminase antibodies (tTG) and anti-endomysial antibody (IgA) analysis. For confirmation a small intestine biopsy can be performed under endoscopy. The Anti-gliadin test has fallen out of favor in recent years due to its lack of specificity and low sensitivity. Additionally, genetic markers such as the HLA phenotypes DQ2 and DQ8 may be helpful as they are found in 99% of people with celiac disease.
Those with celiac disease have a higher mortality due to a risk three to six times higher for developing gastrointestinal cancers and in particular a non-Hodgkin’s lymphoma. Patients with celiac disease need close and routine follow up care. Cancer screening along with routine testing for diabetes, thyroid disease, vitamin deficiencies, anemia and osteoporosis should be performed by their family doctor.
Along with stick avoidance of gluten containing foods, replacement of key nutrients is essential. Those who suffer from celiac disease are prone to deficiencies of iron, calcium, folic acid, vitamin B12 and some fat-soluble vitamins (notably Vitamin D). Therefore, it is good practice to supplement with these vitamins and minerals. There are alternatives to wheat, rye and barley that provide a good balance of fiber and a health supply of vitamins usually associated with the offending grains. While corn, potato, and rice make up the mainstay of starches for celiacs, soybeans, tapioca, arrowroot, carob, buckwheat, millet, amaranth and quinoa are allowable and suitable additions.
A good adjunct to a gluten free diet is a new product on the market offered by BeachBody. This product launched in March 2009 was directed to the health and fitness market as a meal replacement dietary supplement for attaining health weight goals. However, this product is guaranteed gluten free and caries many additional nutrients someone with celiac disease would benefit. Shakeology (www.shakeology.com) has benefits for keeping a celiac patient out of a malnutrition state as it has a health helping of protein (from whey), a well balanced supply of multivitamins and minerals, pre and probiotics, digestive enzymes, fiber and adaptogen herbs. It could conceivably be the healthiest meal of the day for any person suffering from celiac disease.
More information is available about this disease, diagnosis and treatments (including a list of gluten free foods) at the Celiac Disease Foundation web site: www.celiac.org.
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JP Saleeby, MD is an integrative medicine physician and emergency room doctor with years experience in nutritional medicine and a formulator of several dietary supplements on the market. He authored a book on adaptogen herbs entitled Wonder Herbs: A guide to Three Adaptogens (Xlibris) in 2006. He recently reviewed the research study supporting the new meal replacement shake Shakeology for Product Partners. He can be reached for comment at jpsaleeby@aol.com.
Reference:
Presutti, R.J., et al, Celiac Disease, Am Fam Physician 2007; 76:1795-1802.
Pruessner, H., Detecting Celiac Disease in your Patient, Am Fam Physician 1998; 57;1023-1039
© 2009
Thursday, March 26, 2009
Problems with Evidence Based Medicine
EBM changes with the seasons, depending on the latest and greatest medical researched published in the top peer-reviewed journals (Lancet, JAMA, NEJM, etc.) But with recommendations changing so often it is confusing to both clinician and patient.
Example, the core-measures treatment of AMI with beta-blockers... considered STANDARD of care for a few years until more current research determined it to be "bad" for patients. So Practice with Caution and don't be too smitten by all that appears between the pages of medical journals. The Art of Medicine still survives.
The recent contribution in this years JAMA illustrates this point:
Scientific Evidence Underlying the ACC/AHA Clinical Practice Guidelines
JAMA. 2009;301(8):831-841. (Feb. 25, 2009)
Context The joint cardiovascular practice guidelines of the American College of Cardiology (ACC) and the American Heart Association (AHA) have become important documents for guiding cardiology practice and establishing benchmarks for quality of care.
Objective To describe the evolution of recommendations in ACC/AHA cardiovascular guidelines and the distribution of recommendations across classes of recommendations and levels of evidence.
Data Sources and Study Selection Data from all ACC/AHA practice guidelines issued from 1984 to September 2008 were abstracted by personnel in the ACC Science and Quality Division. Fifty-three guidelines on 22 topics, including a total of 7196 recommendations, were abstracted.
Data Extraction The number of recommendations and the distribution of classes of recommendation (I, II, and III) and levels of evidence (A, B, and C) were determined. The subset of guidelines that were current as of September 2008 was evaluated to describe changes in recommendations between the first and current versions as well as patterns in levels of evidence used in the current versions.
Results Among guidelines with at least 1 revision or update by September 2008, the number of recommendations increased from 1330 to 1973 (+48%) from the first to the current version, with the largest increase observed in use of class II recommendations. Considering the 16 current guidelines reporting levels of evidence, only 314 recommendations of 2711 total are classified as level of evidence A (median, 11%), whereas 1246 (median, 48%) are level of evidence C. Level of evidence significantly varies across categories of guidelines (disease, intervention, or diagnostic) and across individual guidelines. Recommendations with level of evidence A are mostly concentrated in class I, but only 245 of 1305 class I recommendations have level of evidence A (median, 19%).
Conclusions Recommendations issued in current ACC/AHA clinical practice guidelines are largely developed from lower levels of evidence or expert opinion. The proportion of recommendations for which there is no conclusive evidence is also growing. These findings highlight the need to improve the process of writing guidelines and to expand the evidence base from which clinical practice guidelines are derived.
Author Affiliations: Division of Cardiology and Duke Clinical Research Institute (Dr Tricoci), Division of General Internal Medicine and Duke Center for Education and Research on Therapeutics (Dr Kramer), and Division of Cardiology and Duke Translational Medicine Institute (Dr Califf), Duke University, Durham, North Carolina; American College of Cardiology Science and Quality Division, Washington, DC (Mr Allen); and Center for Cardiovascular Science and Medicine, University of North Carolina, Chapel Hill (Dr Smith).
Sunday, March 22, 2009
Friday, March 20, 2009
Shakeology Launch at Beach Body Summit '09
Speaking before a crowd of 700+ coaches ....
California (March 14th, 2009). Shakeology the new meal replacement by BeachBody is launched in Hollywood California at the 2009 Coaches Summit. On hand to speak about the science and research behind this amazing new dietary supplement is..........me. I share the podium with Carl Daikeler (CEO of Beachbody) to launch this product. For video click on this link and visit Day 2 of Summit. http://www.beachbody.com/category/video.do?bclid=6615764001








